Back to search

Article

Synora: vector-based boundary detection for spatial omics

2026-03-02

Abstract excerpt

<h4>ABSTRACT</h4> Tumor–stroma boundaries are critical microenvironmental niches where malignant and non-malignant cells exchange signals that shape invasion, immune modulation and therapeutic response. Spatial omics platforms now resolve these interfaces at single-cell scale, but computational boundary detection remains challenging because heterogeneous neighborhoods can arise either from true compartment interf...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6f50230a-0669-5942-865f-22da159d70b5
DOI
10.64898/2026.02.26.708395
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Synora: vector-based boundary detection for spatial omicsDOI 10.64898/2026.02.26.708395
STARComm Scalably Detects Emergent Modules of Spatial Cell-Cell Communication in Inflammation and CancerSemantic proximity
Star-Motifs: Revealing Single-Cell Spatiotypes from Routine Histology Using Star-Convex NeighborhoodsSemantic proximity
N-Orbit: towards a universal model and metric for comparing tissue microenvironmentsSemantic proximity
Toward Computationally Complete Spatial OmicsSemantic proximity
Conserved principles of spatial biology define tumor heterogeneity and response to immunotherapySemantic proximity
SOTIP: a Unified Framework for Microenvironment Modelling with Spatial Omics DataSemantic proximity
Single-cell spatial atlas of high-grade serous ovarian cancer unveils MHC class II as a key driver of spatial tumor ecosystems and clinical outcomesSemantic proximity
Φ-Space ST: a platform-agnostic method to identify cell states in spatial transcriptomics studiesSemantic proximity
geneSCOPE: gene Spatial Co-Occurrence of Pairwise ExpressionSemantic proximity
Cophenetic Spatial Topology Embedding reveals multiscale tissue architecture in spatial omicsSemantic proximity
MOSAIC: Intra-tumoral heterogeneity characterization through large-scale spatial and cell-resolved multi-omics profilingSemantic proximity
High Purity Differential Expression of Genes across Spatial DomainsSemantic proximity
Select a neighboring publication to make it the new centre.