Article

Loss of STIM1 and STIM2 in salivary glands disrupts ANO1 function but does not induce Sjogren’s disease

2024-01-08

Abstract excerpt

Sjogren’s disease (SjD) is an autoimmune disease characterized by xerostomia (dry mouth), lymphocytic infiltration into salivary glands and the presence of SSA and SSB autoantibodies. Xerostomia is caused by hypofunction of the salivary glands and has been involved in the development of SjD. Saliva production is regulated by parasympathetic input into the glands initiating intracellular Ca 2+ signals that activat...

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Literature Corpus work: 6f3624fd-1171-5b4b-96c4-260215a4b431
DOI: 10.1101/2024.01.08.574702

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