Article
Changes in the Submandibular Salivary Gland Epithelial Cell Subpopulations During Progression of Sjögren's Syndrome-Like Disease in the NOD/ShiLtJ Mouse Model.
Anatomical record (Hoboken, N.J. : 2007) - 1 Sept 2015
Gervais Elise M, Desantis Kara A, Pagendarm Nicholas, Nelson Deirdre A, Enger Tone, Skarstein Kathrine, Liaaen Jensen Janicke, Larsen Melinda
Abstract excerpt
Sjögren's syndrome (SS), an autoimmune exocrinopathy, is associated with dysfunction of the secretory salivary gland epithelium, leading to xerostomia. The etiology of SS disease progression is poorly understood as it is typically not diagnosed until late stage. Since mouse models allow the study of disease progression, we investigated the NOD/ShiLtJ mouse to explore temporal changes to the salivary epithelium....
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