Article

Regulatory T cells and IFN-γ-producing Th1 cells play a critical role in the pathogenesis of Sjögren’s Syndrome

2024-01-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Sjögren’s Disease (SjD) is an autoimmune disorder characterized by progressive dysfunction, inflammation and destruction of salivary and lacrimal glands, and by extraglandular manifestations. Its etiology and pathophysiology remain incompletely understood, though a role for autoreactive B cells has been considered key. Here, we investigated the role of effector and regulator...

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Literature Corpus work: bc3833e2-481d-566c-9840-9463c84fa2b7
DOI: 10.1101/2024.01.23.576314

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