Article

Dynamic changes in human single cell transcriptional signatures during fatal sepsis

2021-03-02

Abstract excerpt

Systemic infections, especially in patients with chronic diseases, result in sepsis: an explosive, uncoordinated immune response that can lead to multisystem organ failure with a high mortality rate. Sepsis survivors and non-survivors oftentimes have similar clinical phenotypes or sepsis biomarker expression upon diagnosis, suggesting that the dynamics of sepsis in the critical early stage may have an impact on th...

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Literature Corpus work: 6f26b403-0500-5010-a196-b1844c447dae
DOI: 10.1101/2021.03.01.21252411

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