Article

High-throughput RNA and Single-cell RNA Sequencing to Identify Sepsis associated Molecular Mechanisms and the Blood Immune Cell Landscape

2025-04-04

Abstract excerpt

Sepsis, a leading cause of death in intensive care units (ICUs), is a complex systemic inflammatory response to infection with high morbidity and mortality. Its pathogenesis involves dysregulated inflammation, immune dysfunction, and metabolic alterations, particularly in lactate metabolism. This study employed bioinformatics analyses to explore sepsis mechanisms and identify potential therapeutic targets. We anal...

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Literature Corpus work: 84922427-7bbc-5bca-b593-a309dff14d0a
DOI: 10.1101/2025.03.31.646322

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