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Article

Single-cell transcriptomics reveals the alteration of peripheral blood mononuclear cells driven by sepsis

1 Feb 2020

Abstract excerpt

BACKGROUND: Sepsis is a serious systemic inflammatory response syndrome caused by infection, with an extremely high mortality rate. Peripheral blood mononuclear cells (PBMCs) played a key role in the immune response against infection, whose components and functions were altered radically in Sepsis. Here, we wondered to characterize the alteration of PBMCs in sepsis at the single-cell transcriptional level....

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Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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PMID: 32175418
DOI: 10.21037/atm.2020.02.35

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