Article

Analysis of novel biomarkers and immune cell alterations in sepsis based on single-cell sequencing and machine learning algorithms

2023-07-13

Abstract excerpt

We aim to investigate the changes of the immune milieu during sepsis and screen out novel biomarkers with favor diagnostic value using single-cell sequencing and machine learning algorithms. Two gene-chip datasets (GSE28750 and GSE95233) and two single-cell sequencing datasets (GSE167363 and GSE195965) were obtained from the GEO database. We used “ limma ” package in R software to screen out differentially express...

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Literature Corpus work: c2ed80eb-7d01-513d-af46-3a3cfe0e7b32
DOI: 10.21203/rs.3.rs-3139286/v1

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