Article

Correlation-based and feature-driven mutation signature analyses to identify genetic features associated with DNA mutagenic processes in cancer genomes

2020-01-06

Abstract excerpt

Mutation signatures represent unique sequence footprints of somatic mutations resulting from specific DNA mutagenic and repair processes; however, their causal associations and potential utility for genome research remain largely unknown. In this study, we performed PanCancer-scale correlative analyses to identify the genomic features associated with tumor mutation burdens (TMB) and individual mutation signatures....

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Literature Corpus work: 6f1881ca-11d6-50a1-b9be-a0ee9ef2b434
DOI: 10.1101/2020.01.06.895698

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