Article

Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer

2019-03-05

Abstract excerpt

Studies of cancer mutations typically focus on identifying cancer driving mutations. However, in addition to the mutations that confer a growth advantage, cancer genomes accumulate a large number of passenger somatic mutations resulting from normal DNA damage and repair processes as well as mutations triggered by carcinogenic exposures or cancer related aberrations of DNA maintenance machinery. These mutagenic pro...

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Literature Corpus work: f70a6e19-2b3a-557e-bc42-a68da5f4defd
DOI: 10.1101/568568

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