Article

An Information Theoretic Framework for Protein Activity Measurement

2021-10-02

Abstract excerpt

Nonparametric analytical Rank-based Enrichment Analysis (NaRnEA) is a novel gene set analysis method which leverages an analytical null model derived under the Principle of Maximum Entropy. NaRnEA critically improves over two widely used methods – Gene Set Enrichment Analysis (GSEA) and analytical Rank-based Enrichment Analysis (aREA) – as shown by differential activity measurement of ~2,500 transcriptional regula...

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Literature Corpus work: 6ec8dbca-d82a-5dc6-87ac-693619a34b49
DOI: 10.1101/2021.10.02.462873

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