Article
Sensitivity analysis of gene ranking methods in phenotype prediction.
Journal of biomedical informatics - 1 Dec 2016
deAndrés-Galiana Enrique J, Fernández-Martínez Juan L, Sonis Stephen T
Abstract excerpt
INTRODUCTION: It has become clear that noise generated during the assay and analytical processes has the ability to disrupt accurate interpretation of genomic studies. Not only does such noise impact the scientific validity and costs of studies, but when assessed in the context of clinically translatable indications such as phenotype prediction, it can lead to inaccurate conclusions that could ultimately impact...
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