Article

PLAID: ultrafast single-sample gene set enrichment scoring

2025-06-20

Abstract excerpt

<h4>Motivation</h4> In recent years, computational methods have emerged that calculate enrichment of gene signatures within individual samples, rather than across pooled samples. These signatures offer critical insights into the coordinated activity of functionally related genes, proteins or metabolites, enabling identification of unique molecular profiles based on gene set and pathway activity in individual cell...

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Literature Corpus work: 5b33b50a-4e9f-5e04-879f-bb28f98cc2ec
DOI: 10.1101/2025.06.14.659661

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