Article

CLEAR: Concise List Enrichment Analysis Reducing Redundancy

2026-04-01

Abstract excerpt

<h4>Motivation</h4> High-throughput experiments generate genome-wide measurements for thousands of genes, which are often tested marginally. Biological processes are driven by coordinated groups of genes rather than individual genes, making gene set enrichment analysis an essential post hoc interpretation tool. Traditional approaches such as Over-Representation Analysis and Gene Set Enrichment Analysis test gene...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4ec0704c-2397-5d71-bdff-219892922053
DOI: 10.64898/2026.03.30.715378

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CLEAR: Concise List Enrichment Analysis Reducing RedundancyDOI 10.64898/2026.03.30.715378Read

BAGSE: a Bayesian hierarchical model approach for gene set enrichment analysisSemantic proximity Read

Towards a gold standard for benchmarking gene set enrichment analysisSemantic proximity Read

Combining multiple tools outperforms individual methods in gene set enrichment analysesSemantic proximity Read

Comparative study of gene set enrichment methods.Semantic proximity Read

Cutting through the clutter: minimizing redundancy in GO enrichment analysis with evoGOSemantic proximity Read

RichPathR: a gene set enrichment analysis and visualization toolSemantic proximity Read

Enhancing gene set enrichment using networksSemantic proximity Read

PLAID: ultrafast single-sample gene set enrichment scoringSemantic proximity Read

Fold-change-Specific Enrichment Analysis (FSEA): Quantification of Transcriptional Response Magnitude for Functional Gene GroupsSemantic proximity Read

Identifying gene interaction enrichment for gene expression data.Semantic proximity Read

ReString – Automating Functional Enrichment Retrieval and Results AggregationSemantic proximity Read

GeneWalk identifies relevant gene functions for a biological context using network representation learningSemantic proximity Read