Article
ActivePPI: quantifying protein-protein interaction network activity with Markov random fields.
Bioinformatics (Oxford, England) - 2 Sept 2023
Wang Chuanyuan, Xu Shiyu, Sun Duanchen, Liu Zhi-Ping
Abstract excerpt
MOTIVATION: Protein-protein interactions (PPI) are crucial components of the biomolecular networks that enable cells to function. Biological experiments have identified a large number of PPI, and these interactions are stored in knowledge bases. However, these interactions are often restricted to specific cellular environments and conditions. Network activity can be characterized as the extent of agreement...
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