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Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q<sup>58</sup>-K<sup>59</sup> Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities

2018-06-15

Abstract excerpt

In the recent past about 40 botulinum neurotoxin (BoNT) subtypes belonging to serotypes A, B, E, and F pathogenic to humans were identified among hundreds of independent isolates. BoNTs are the etiological factors of botulism and represent potential bioweapons, but are also recognized pharmaceuticals for efficient counteraction of hyperactive nerve terminals in a variety of human diseases. The detailed biochemical...

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Literature Corpus work
6ea91f0a-d65a-5624-a823-22f03b8bd87a
DOI
10.20944/preprints201806.0244.v1
Open publication

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Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q<sup>58</sup>-K<sup>59</sup> Peptide Bond Exhibit Unique Catalytic Properties and Substrate SpecificitiesDOI 10.20944/preprints201806.0244.v1
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