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Article

Comparison of the catalytic properties of the botulinum neurotoxin subtypes A1 and A5.

Biochimica et biophysica acta - 1 Dec 2013

Wang Dongxia, Krilich Joan, Pellett Sabine, Baudys Jakub, Tepp William H, Barr John R, Johnson Eric A, Kalb Suzanne R

Abstract excerpt

Clostridium botulinum neurotoxins (BoNTs) cause the life-threatening disease botulism through the inhibition of neurotransmitter release by cleaving essential SNARE proteins. There are seven serologically distinctive types of BoNTs and many subtypes within a serotype have been identified. BoNT/A5 is a recently discovered subtype of type A botulinum neurotoxin which possesses a very high degree of sequence...

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Identifiers

PMID: 24096023
DOI: 10.1016/j.bbapap.2013.09.007
PMCID: PMC4582773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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