Article

Conformational plasticity of the human norovirus GII.3 capsid reveals alternative P domain interaction networks

2026-06-25

Abstract excerpt

Human noroviruses (HuNoVs) are a leading cause of acute gastroenteritis worldwide, yet no effective antiviral therapeutics are currently available. Although environmentally induced capsid conformational changes associated with infectivity have been reported in murine noroviruses (MNVs), comparable conformational switching has not been demonstrated in HuNoVs. In this study, we generated HuNoV GII.3 virus-like parti...

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Literature Corpus work: 6e8813e8-00ae-58f8-a8f3-acaa7744d91d
DOI: 10.64898/2026.06.25.734440

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