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High-Resolution Cryo-EM Reveals Dynamics in the Murine Norovirus Capsid

2019-07-04

Abstract excerpt

Rather than acting as rigid symmetrical shells to protect and transmit their genomes, the capsids of non-enveloped, icosahedral viruses co-ordinate multiple, essential processes during the viral life-cycle, and undergo extensive conformational rearrangements to deliver these functions. Capturing conformational flexibility has been challenging, yet could be key in understanding and combating infections that viruses...

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Literature Corpus work
07138a54-fe4b-5e39-9394-5197d7a1781d
DOI
10.1101/693143
Open publication

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High-Resolution Cryo-EM Reveals Dynamics in the Murine Norovirus CapsidDOI 10.1101/693143
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