Article
Mechanisms seeding the emergence of new piRNAs.
Trends in genetics : TIG - 1 Sept 2026
Mitjavila-Ventura Adrià, Vavouri Tanya
Abstract excerpt
PIWI-interacting RNAs (piRNAs) form an adaptive small RNA system that regulates transposons and some host genes in animal gonads. In this forum, we discuss recent within-species comparisons across flies and mammals that reveal extensive variation in piRNA-producing loci, providing new insights into how piRNAs emerge, diversify, and adapt to new threats.
Read the complete abstract on PubMedTopics
- Animals
- Piwi-Interacting RNA
- DNA Transposable Elements
- Evolution, Molecular
- Humans
- RNA, Small Interfering
- Drosophila
- Genetic Variation
