Article

Ribosomal stress-induced senescence as a novel pro-senescence strategy for p16 positive basal-like breast cancer

2018-11-14

Abstract excerpt

<h4>ABSTRACT</h4> Re-engaging the senescent programme represents an attractive yet underexplored strategy for cancer therapy, particularly for those tumour subtypes where targeted agents are limited or unavailable. Here, we identify a specific subset of ribosomal proteins as novel pro-senescence therapeutic targets for a highly aggressive subtype of breast cancer, p16 positive basal-like breast cancer. Mechanisti...

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Literature Corpus work: 6df0f9b4-bf6c-5157-a8c7-1a4cec895dde
DOI: 10.1101/469445

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