Article

Breast cancer risk based on a deep learning predictor of senescent cells in normal tissue

2023-05-23

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> The ability to predict future risk of cancer development in non-malignant biopsies is poor. Cellular senescence has been associated with cancer as either a barrier mechanism restricting autonomous cell proliferation or a tumor-promoting microenvironmental mechanism that secretes pro-inflammatory paracrine factors. With most work done in non-human models and the heterogenous nat...

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Literature Corpus work: e613b684-4990-577f-bc8f-22b68c80033d
DOI: 10.1101/2023.05.22.23290327

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