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Article

Therapy-induced senescence in breast cancer: an overview

25 Jul 2024

Abstract excerpt

Outcomes for women with breast cancer have improved dramatically in recent decades. However, many patients present with intrinsic drug resistance and others are initially sensitive to anti-cancer drugs but acquire resistance during the course of their treatment, leading to recurrence and/or metastasis. Drug therapy-induced senescence (TIS) is a form of drug resistance characterised by the induction of cell cycle...

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PMID: 39280248
DOI: 10.37349/etat.2024.00254

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