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Metabolic, autophagic, and mitophagic activities in cancer initiation and progression

1 Apr 2016

Abstract excerpt

Cancer is a complex disease marked by uncontrolled cell growth and invasion. These processes are driven by the accumulation of genetic and epigenetic alterations that promote cancer initiation and progression. Contributing to genome changes are the regulation of oxidative stress and reactive species-induced damage to molecules and organelles. Redox regulation, metabolic plasticity, autophagy, and mitophagy play...

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Share to Autophagy in Disease and Therapy
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27372165
DOI: 10.1016/j.bj.2015.10.002

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