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Therapeutic Potential of Tumor Metabolic Reprogramming in Triple-Negative Breast Cancer

8 Apr 2023

Abstract excerpt

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, with clinical features of high metastatic potential, susceptibility to relapse, and poor prognosis. TNBC lacks the expression of the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). It is characterized by genomic and transcriptional heterogeneity and a tumor...

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PMID: 37108109
DOI: 10.3390/ijms24086945

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