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Article

Role of autophagy in cancer-associated fibroblast activation, signaling and metabolic reprograming

3 Jan 2024

Abstract excerpt

Tumors not only consist of cancerous cells, but they also harbor several normal-like cell types and non-cellular components. cancer-associated fibroblasts (CAFs) are one of these cellular components that are found predominantly in the tumor stroma. Autophagy is an intracellular degradation and quality control mechanism, and recent studies provided evidence that autophagy played a critical role in CAF formation,...

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PMID: 38234683
DOI: 10.3389/fcell.2023.1274682

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