Article

The TRIM-NHL protein NHL-2 is a Novel Co-Factor of the CSR-1 and HRDE-1 22G-RNA Pathways

2018-02-05

Abstract excerpt

<h4>ABSTRACT</h4> Proper regulation of germline gene expression is essential for fertility and maintaining species integrity. In the C. elegans germline, a diverse repertoire of regulatory pathways promote the expression of endogenous germline genes and limit the expression of deleterious transcripts to maintain genome homeostasis. Here we show that the conserved TRIM-NHL protein, NHL-2, plays an essential role...

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Literature Corpus work: 6da072db-d99f-5e56-8bae-b47d96a760b5
DOI: 10.1101/260240

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