Article
A microRNA family exerts maternal control on sex determination in C. elegans.
Genes & development - 15 Feb 2017
McJunkin Katherine, Ambros Victor
Abstract excerpt
Gene expression in early animal embryogenesis is in large part controlled post-transcriptionally. Maternally contributed microRNAs may therefore play important roles in early development. We elucidated a major biological role of the nematode mir-35 family of maternally contributed essential microRNAs. We show that this microRNA family regulates the sex determination pathway at multiple levels, acting both...
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