Article
A novel RNAseq-assisted method for MHC class I genotyping in a non-model species applied to a lethal vaccination-induced alloimmune disease.
BMC genomics - 17 May 2016
Demasius Wiebke, Weikard Rosemarie, Hadlich Frieder, Buitkamp Johannes, Kühn Christa
Abstract excerpt
BACKGROUND: MHC class I genotyping is essential for a wide range of biomedical, immunological and biodiversity applications. Whereas in human a comprehensive MHC class I allele catalogue is available, respective data in non-model species is scarce in spite of decades of research. RESULTS: Taking advantage of the new high-throughput RNA sequencing technology (RNAseq), we developed a novel RNAseq-assisted method...
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