Article

Regulation of HPV 16-E7 by E2, phosphorylation and the proteasome

2007-01-01

Abstract excerpt

In order to ensure a productive life cycle, Human Papillomaviruses (HPVs) require fine regulation of their gene products. Uncontrolled activity of the viral oncoproteins, E6 and E7, results in the immortalisation of the infected epithelial cells and thus prevents the production of mature virions. Here, we investigate the regulation of HPV-16 E7 activities through its interaction with both viral and cellular gene p...

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Literature Corpus work: 6d75fef4-0a69-590c-8d52-b2f70b58c4e6
DOI: 10.21954/ou.ro.0000fd51

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