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Article

Identification and Functional Characterization of Phosphorylation Sites of the Human Papillomavirus 31 E8^E2 Protein.

Journal of virology - 15 Feb 2018

van de Poel Saskia, Dreer Marcel, Velic Ana, Macek Boris, Baskaran Praveen, Iftner Thomas, Stubenrauch Frank

Abstract excerpt

The papillomavirus E2 protein regulates transcription, replication, and nuclear retention of viral genomes. Phosphorylation of E2 in the hinge region has been suggested to modulate protein stability, DNA-binding activity, and chromosomal attachment. The papillomavirus E8^E2 protein shares the hinge domain with E2 and acts as a repressor of viral replication. Mass spectrometry analyses of human papillomavirus 31...

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Identifiers

PMID: 29167339
DOI: 10.1128/JVI.01743-17
PMCID: PMC5790924

Genes

LYPD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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