Article

Focal and diffuse clinical subtypes in early-stage Parkinson’s disease: a one-year longitudinal study

2022-08-09

Abstract excerpt

<title>Abstract</title> <p>Heterogeneity in Parkinson’s disease (PD) presents a barrier to understanding disease mechanisms and developing new treatments. This challenge may be partially overcome by stratifying patients into clinically meaningful subtypes. A recent subtyping scheme classifies de novo PD patients into three subtypes: mild-motor predominant, intermediate, or diffuse-malignant, based on motor impair...

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Literature Corpus work: c361c757-8e15-5490-aea0-df4833513b49
DOI: 10.21203/rs.3.rs-1870271/v1

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