Delineating nonmotor symptoms in early Parkinson's disease and first-degree relatives.

doi:10.1002/mds.26281

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Article

Delineating nonmotor symptoms in early Parkinson's disease and first-degree relatives.

Movement disorders : official journal of the Movement Disorder Society - 1 Nov 2015

Baig Fahd, Lawton Michael, Rolinski Michal, Ruffmann Claudio, Nithi Kannan, Evetts Samuel G, Fernandes Hugo R, Ben-Shlomo Yoav, Hu Michele T M

Abstract excerpt

Nonmotor symptoms (NMS) are an important prodromal feature of Parkinson's disease (PD). However, their frequency, treatment rates, and impact on health-related quality of life (HRQoL) in the early motor phase is unclear. Rates of NMS in enriched at-risk populations, such as first-degree PD relatives, have not been delineated. We assessed NMS in an early cohort of PD, first-degree PD relatives and control subjects...

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Adult
Aged
Aged, 80 and over
Autonomic Nervous System Diseases
Cognition Disorders
Depression
Family
Female
Humans
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mental Disorders

Middle Aged

Mutation

Olfaction Disorders

Parkinson Disease

Protein Serine-Threonine Kinases

Quality of Life

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PMID: 26179331
DOI: 10.1002/mds.26281
PMCID: PMC5034839

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