Article

Somatic-to-primordial Germ Cell-Like Transformation is Critical in Tumour Initiation of Mouse Breast Tumour 4T1 Cells

2022-11-04

Abstract excerpt

It has been proposed that tumourigenicity was an intrinsic feature of embryonic/germ cell developmental axis as well as embryonic/germ cell-related genes play a crucial role in tumourigenicity. Our previous studies indicated that primordial germ cell (PGC)-like potential could be reactivated in tumourigenesis. In this study, 4T1, 168FARN and 67NR cells which originated from the same mouse breast cancer were studie...

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Literature Corpus work: 6cd7a781-b8ba-5321-a7dd-ff9ced15aaca
DOI: 10.20944/preprints202211.0080.v1

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