Article

Activation of embryonic/germ cell-like axis links poor outcomes of gliomas

2022-02-21

Abstract excerpt

<h4>Background: </h4> It is unclear which core events drive the malignant progression of gliomas. Earlier studies have revealed that the embryonic stem (ES) cell/early PGC state is associated with tumourigenicity. This study was designed to investigate the role of ES/PGC state in poor outcomes of gliomas. <h4>Methods: </h4> Crispr-Cas9 technology, RT-PCR and animal experiments were used to investigate whether PGC-...

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Literature Corpus work: 33bca1ed-119b-5cf3-89c4-d7746d29fcb0
DOI: 10.21203/rs.3.rs-550958/v2

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