Article
Spontaneous metastasis in mouse models of testicular germ-cell tumours.
International journal of andrology - 1 Aug 2011
Zechel J L, MacLennan G T, Heaney J D, Nadeau J H
Abstract excerpt
Testicular germ-cell tumours (TGCTs) are the most common cancer in young men; the incidence is increasing worldwide and they have an unusually high rate of metastasis. Despite significant work on TGCTs and their metastases in humans, absence of a mouse model of spontaneous metastasis has greatly limited our understanding of the mechanisms by which metastatic potential is acquired and on their modes of...
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