Article
Association between cancer genes and germ layer specificity.
Medical oncology (Northwood, London, England) - 29 Sept 2022
Lee Hwayeong, Lee Sungwhan, Cho Woo Jong, Shin Minjung, Park Leeyoung
Abstract excerpt
Cancer signaling pathways defining cell fates are related to differentiation. During the developmental process, three germ layers (endoderm, mesoderm, and ectoderm) are formed during embryonic development that differentiate into organs via the epigenetic regulation of specific genes. To examine the relationship, the specificities of cancer gene mutations that depend on the germ layers are studied. The major...
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