Article

Loss of Dead end1 induces testicular teratomas from primordial germ cells that failed to undergo sexual differentiation in embryonic testes

2023-01-06

Abstract excerpt

<title>Abstract</title><p>Spontaneous testicular teratomas (STTs) are tumours comprising a diverse array of cell and tissue types, which are derived from pluripotent stem-like cells called embryonal carcinoma cells (ECCs). Although mouse ECCs originate from primordial germ cells (PGCs) in embryonic testes, the molecular basis underlying ECC development remains unclear. This study shows that the conditional deletio...

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Literature Corpus work: f25f6800-7b6f-55b3-b272-57bfb3704071
DOI: 10.21203/rs.3.rs-2403208/v1

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