Article
129/Sv mice--a model system for studying germ cell biology and testicular cancer.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2001
Jiang L I, Nadeau J H
Abstract excerpt
Some forms of testicular germ cell tumors (TGCTs) arise from primordial germ cells (PGCs) during fetal development. In both humans and mice, genetic control of susceptibility is complex, involving both Mendelian and polygenic factors. Identification and characterization of TGCT genes will provide insight not only into the basis for inherited susceptibility, but also into the genetic control of the development of...
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