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Article

PARP14 is a writer, reader and eraser of mono-ADP-ribosylation

2023-06-24

Abstract excerpt

PARP14/BAL2 is a large multidomain enzyme involved in signaling pathways with relevance to cancer, inflammation, and infection. Inhibition of its mono-ADP-ribosylating PARP homology domain and its three ADP-ribosyl binding macro domains has been regarded as a potential means of therapeutic intervention. Macrodomains-2 and -3 are known to stably bind to ADP-ribosylated target proteins; but the function of macrodoma...

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Literature Corpus work
6bda8827-0eb9-50fc-be49-976eced0c93c
DOI
10.1101/2023.06.24.546374
Open publication

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PARP14 is a writer, reader and eraser of mono-ADP-ribosylationDOI 10.1101/2023.06.24.546374
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