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Article

Rapid Evolution of PARP Genes Suggests a Broad Role for ADP-Ribosylation in Host-Virus Conflicts

29 May 2014

Abstract excerpt

Post-translational protein modifications such as phosphorylation and ubiquitinylation are common molecular targets of conflict between viruses and their hosts. However, the role of other post-translational modifications, such as ADP-ribosylation, in host-virus interactions is less well characterized. ADP-ribosylation is carried out by proteins encoded by the PARP (also called ARTD) gene family. The majority of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24875882
DOI: 10.1371/journal.pgen.1004403

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