Article

Transcriptome-Proteome analysis of human naive and memory B cell subsets reveal isotype and subclass-specific phenotypes

2025-06-08

Abstract excerpt

Antibodies produced by B cells aid in recognition and clearance of pathogens and is the cornerstone of vaccination strategies. Humans produce nine different antibody isotypes and their effector functions differ according to the type of antigen and route of exposure. Phenotypic variation between isotype-switched B cell subsets is expected but not studied in detail. To obtain a molecular definition of isotype-define...

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Literature Corpus work: 6bc7713c-6429-5cdc-bf92-fb98f61d552d
DOI: 10.1101/2025.06.05.657894

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