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Article

An integrated multi-omic single cell atlas to redefine human B cell memory

2019-10-13

Abstract excerpt

To evaluate the impact of heterogeneous B cells in health and disease, comprehensive profiling is needed at a single cell resolution. We developed a highly-multiplexed screen to quantify the co-expression of 351 surface molecules on low numbers of primary cells. We identified dozens of differentially expressed molecules and aligned their variance with B cell isotype usage, metabolism, biosynthesis activity, and si...

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Literature Corpus work
46db2c44-d131-509a-8e7b-8e98fd983010
DOI
10.1101/801530
Open publication

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An integrated multi-omic single cell atlas to redefine human B cell memoryDOI 10.1101/801530
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