Article

Persistent SARS-CoV-2 infection and increasing viral variants in children and young adults with impaired humoral immunity

2021-03-02

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> There is increasing concern that persistent infection of SARS-CoV-2 within immunocompromised hosts could serve as a reservoir for mutation accumulation and subsequent emergence of novel strains with the potential to evade immune responses. <h4>Methods</h4> We describe three patients with acute lymphoblastic leukemia who were persistently positive for SARS-CoV-2 by real-time...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6ba5aa8e-2563-5c00-a217-eed63fdb28bc
DOI: 10.1101/2021.02.27.21252099

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Persistent SARS-CoV-2 infection and increasing viral variants in children and young adults with impaired humoral immunityDOI 10.1101/2021.02.27.21252099Read

Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series.Semantic proximity Read

Extensive Intra-host evolution and T cell escape by SARS-CoV-2 in a 2.5-year persistent infection of an immunocompromised hostSemantic proximity Read

SARS-CoV-2 shedding, infectivity and evolution in an immunocompromised adult patientSemantic proximity Read

COVID-19 in an immunocompromised host: persistent shedding of viable SARS-CoV-2 and emergence of multiple mutations: a case report.Semantic proximity Read

Emergence of multiple SARS-CoV-2 mutations in an immunocompromised hostSemantic proximity Read

Prolonged Infectious SARS-CoV-2 Shedding from an Immunocompromised PatientSemantic proximity Read

Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host.Semantic proximity Read

Year-long COVID-19 infection reveals within-host evolution of SARS-CoV-2 in a patient with B cell depletionSemantic proximity Read

SARS-CoV-2 evolution during prolonged infection in immunocompromised patientsSemantic proximity Read

SARS-CoV-2 population dynamics in immunocompetent individuals in a closed transmission chain shows genomic diversity over the course of infection.Semantic proximity Read

Molecular Characterization of Persistent SARS-CoV-2 Infections in Immunocompromised Patients.Semantic proximity Read

Case reports of persistent SARS-CoV-2 infection outline within-host viral evolution in immunocompromised patients.Semantic proximity Read