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<i>Ahr</i> and <i>Cyp1a2</i> genotypes both affect susceptibility to motor deficits following gestational and lactational exposure to polychlorinated biphenyls

2017-09-04

Abstract excerpt

Polychlorinated biphenyls (PCBs) are persistent organic pollutants known to cause adverse health effects and linked to neurological deficits in both human and animal studies. Children born to exposed mothers are at highest risk of learning and memory and motor deficits. We developed a mouse model that mimics human variation in the aryl hydrocarbon receptor and cytochrome P450 1A2 (CYP1A2) to determine if genetic v...

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Literature Corpus work
6b81e9ee-e6df-5ca2-b83c-e6e8f54e7488
DOI
10.1101/184010
Open publication

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<i>Ahr</i> and <i>Cyp1a2</i> genotypes both affect susceptibility to motor deficits following gestational and lactational exposure to polychlorinated biphenylsDOI 10.1101/184010
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