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Expression of the Human R163C-<em>RYR1</em> Gain-of-Function Mutation Modified 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) Developmental Neurotoxicity in Weanling Mice

2026-08-04

Abstract excerpt

Epidemiological studies have identified the developing brain as a target of concern for polychlorinated biphenyls (PCBs). In animal models, behavioral deficits caused by developmental exposure to PCBs have been associated with altered patterns of dendritic arborization in functionally relevant brain regions. In vitro studies revealed that PCB 95 promoted dendritic growth in primary rat hippocampal neuron-glia co-c...

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Literature Corpus work
22b19aa3-6fee-510a-bf17-3663868372a2
DOI
10.20944/preprints202608.0240.v1
Open publication

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Expression of the Human R163C-<em>RYR1</em> Gain-of-Function Mutation Modified 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) Developmental Neurotoxicity in Weanling MiceDOI 10.20944/preprints202608.0240.v1
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