Article

Humanized <i>CYP2C19</i> transgenic mouse as an animal model of cerebellar ataxia

2022-01-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Animal models are essential for understanding etiology and pathophysiology of movement disorders. Previously, we have found that mice transgenic for the human CYP2C19 gene, expressed in the liver and developing brain, exhibit altered neurodevelopment associated with impairments of their motor function and emotionality. <h4>Objectives</h4> To characterize motoric phenotype...

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Literature Corpus work: 3b823147-22b4-543e-98de-86e54e058278
DOI: 10.1101/2022.01.10.475612

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