Article

Defective Mitochondrial Respiration in Hereditary Thoracic Aneurysms

2025-04-02

Abstract excerpt

Thoracic Aortic Aneurysms are life-threatening vascular conditions linked to inherited disorders such as Marfan syndrome, Loeys-Dietz syndrome, vascular Ehlers-Danlos syndrome, and Familial Thoracic Aortic Aneurysms and Dissections. While traditionally associated with extracellular matrix and contractile defects in vascular smooth muscle cells, emerging evidence suggests a key role for mitochondrial dysfunction. H...

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Literature Corpus work: 6b338d15-0eac-581f-9f73-137157185452
DOI: 10.20944/preprints202504.0244.v1

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