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Article

Mitochondrial Dysfunction in Vascular Wall Cells and Its Role in Atherosclerosis.

International journal of molecular sciences - 20 Aug 2021

Salnikova Diana, Orekhova Varvara, Grechko Andrey, Starodubova Antonina, Bezsonov Evgeny, Popkova Tatyana, Orekhov Alexander

Abstract excerpt

Altered mitochondrial function is currently recognized as an important factor in atherosclerosis initiation and progression. Mitochondrial dysfunction can be caused by mitochondrial DNA (mtDNA) mutations, which can be inherited or spontaneously acquired in various organs and tissues, having more or less profound effects depending on the tissue energy status. Arterial wall cells are among the most vulnerable to...

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Source

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Identifiers

PMID: 34445694
DOI: 10.3390/ijms22168990
PMCID: PMC8396504

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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