Article
Mitochondrial mutations in atherosclerosis: new solutions in research and possible clinical applications.
Current pharmaceutical design - 1 Jan 2013
Sobenin Igor A, Chistiakov Dimitry A, Bobryshev Yuri V, Postnov Anton Y, Orekhov Alexander N
Abstract excerpt
Cardiovascular diseases are the leading causes of morbidity and mortality in many industrialized societies. Atherosclerosis is the major risk factor for the development of cardiovascular disease based on arterial endothelial dysfunction caused by the impairment of endothelial-dependent dilation. Atherosclerosis is a complex vascular disease resulted from the harmful interactions between genetic and environmental...
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